Robert P. Bowser, PhD, has dedicated his professional career to elaborating the molecular mechanisms of neurodegeneration and dissecting the biomarkers of neurodegenerative diseases. Dr. Bowser is currently the Chairman of Neurobiology and a Professor of Neurology and Neurobiology at the Barrow Neurological Institute and St. Joseph’s Hospital and Medical Center in Phoenix, Arizona, where he has worked for over 7 years. There, he directs the Gregory W. Fulton ALS and Neuromuscular Research Center, where he leads research to determine the underlying mechanisms of ALS, identifying new targets for drug treatment, and developing improved therapies for ALS treatment and clinical research studies. Formerly he was the director of both the ALS Tissue Bank and the Center for ALS Research, University of Pittsburgh. An internationally renowned leader in ALS research, Dr. Bowser has contributed to pioneering efforts to discover and validate biomarkers for ALS. This groundbreaking research provides crucial diagnostic indicators of neurodegenerative disease, the molecular mechanisms of motor neuron cell death in ALS, predictors of disease progression, and measures of drug efficacy in clinical trials. His work in these areas has resulted in 5 patents, including biomarkers for the diagnosis of ALS and motor neuron disease, and for neuroendocrine system modulation as a therapy for motor neuron disease. Dr. Bowser has extensive experience in the translation of basic science discoveries to the clinic to improve patient outcomes.
Dr. Bowser earned his PhD in Cell biology from Yale, and was a Postdoctoral Fellow in pathology at the Albert Einstein College of Medicine. He holds a Certificate of Entrepreneurship from the Katz School of Business at the University of Pittsburgh. A member of several editorial boards, including the International Journal of Clinical and Experimental Medicine, Dr. Bowser has published extensively in the areas of proteomics, biomarkers of human disease, diagnostics, and translational neuroscience. He is the 2016 recipient of the IBM Big Data and Analytics Hero award, recognizing his novel application of artificial intelligence in neurodegenerative disease research to identify undiscovered RNA binding proteins altered in ALS. In 2015 the American Academy of Neurology and the ALS Association conferred upon Dr. Bowser the Sheila Essey Award in recognition of his significant research contributions in the search for the cause, prevention of and cure for ALS.